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KMID : 0043319880110010045
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Archives of Pharmacal Research
1988 Volume.11 No. 1 p.45 ~ p.51
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Quantitative Analysis by Derivative Spetrophotometry (III) -Simultaneous quantitation of vitamin B group and vitamin C in by multiple linear regression analysis-
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Park MK
Cho JH
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Abstract
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The feature of resolution enhancement by derivative operation is linked to one of the multivariate analysis, which is multiple linear regression with two options, all-possible and stepwise regression. Examined samples were synthetic mixtures of 5 vitamins, thiamine mononitrate, riboflavin phosphate, nicotinamide, pyridoxine hydrochloride and ascorbic acid. All components in mixture were quantified with reasonably good accuracy and precision. Whole data processing procedure was accomplished on-line by the development of three computer programs written in APPLESOFT BASIC language.
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